Results: Three hundred and eight osteosarcoma cases, 598 leukemia controls, and 604 CNS tumor controls met selection criteria and were assigned a corresponding PWS fluoride level. PWS fluoride level was not associated with osteosarcoma, either in a univariable...
The authors reviewed scientific evidence to inform Ireland Department of Health with regard to any impact, positive and or negative, on the general health of those exposed to community water fluoridation at the levels of 0.4-1.5 ppm. Based on the existing literature...
In response to concerns over the possible carcinogenicity of fluoride compounds added to drinking water raised by the results of a recent animal experiment, we evaluated 36 years of US.cancer mortality data and 15 years of cancer incidence data from two...
Results: The study analysed 2566 osteosarcoma and 1650 Ewing sarcoma cases. There was no evidence of an association between osteosarcoma risk and fluoride in drinking water [relative risk (RR) per one part per million increase in the level of fluoride = 1·001; 90%...
Results: We found no sex-specific statistical differences in the national incidence rates in the younger groups (5–9, 10–14), although 15–19 males were at higher risk to osteosarcoma than females in the same age group (p < 0.001). Sex and age group specific...
The association between fluoride and risk for osteosarcoma is controversial. The purpose of this study was to determine if bone fluoride levels are higher in individuals with osteosarcoma. Incident cases of osteosarcoma (N = 137) and tumor controls (N = 51) were...
