Research
Here you will find evidence based information on fluoride and all aspects of water fluoridation including: water fluoridation and infant formula, support for water fluoridation, cost and cost effectiveness of water fluoridation, water fluoridation and the environment, the dental benefits of water fluoridation, the effects on general health, dental health, health inequalities, and dental fluorosis.
Prenatal exposure to fluoride and neuropsychological development in early childhood: 1-to 4 years
Effect on Early Childhood Caries (2019)
Fluoridated Water Modifies Effect of Breastfeeding on Dental Caries
Breastfeeding is important for health and development. Yet, the interaction between breastfeeding duration and usage of fluoridated water on caries experience has not been investigated. This study examined exposure to fluoridation as an effect modifier of the association between breastfeeding duration and caries. The 2012 to 2014 national population-based study of Australian children involved parental questionnaires and oral epidemiological assessment. Children were grouped by parent-reported breastfeeding duration into minimal (none or <1 mo), breastfed for 1 to <6 mo, breastfed for 6 to 24 mo, and sustained (>24 mo). Residential history and main water source used for the first 2 y of life were collected to group children into exposed (WF) and nonexposed (NF) to fluoridation. Socioeconomic status, infant formula feeding, and sugar-sweetened beverage (SSB) consumption data were collected.
Consequences of water fluoridation cessation in Juneau, Alaska
These results expand our understanding of caries epidemiology under CWF cessation conditions and reaffirm that optimal CWF exposure prevents dental decay. These findings can offer fiscal estimates of the cost burden associated with CWF cessation policies and help decision-makers advance oral health, prevent dental caries, and promote equity in oral health outcomes.
Bashash ADHD Review
synopsis bashash 2018 prenatal fluoride and adhd.pdfDownload
Water Fluoridation and Dental Caries in U.S. Children.. (Slade 2018)
Abstract
Fluoridation of America’s drinking water was among the great public health achievements of the 20th century. Yet there is a paucity of studies from the past 3 decades investigating its dental health benefits in the U.S. population. This cross-sectional study sought to evaluate associations between availability of community water fluoridation (CWF) and dental caries experience in the U.S. child and adolescent population. County-level estimates of the percentage of population served by CWF (% CWF) from the Centers for Disease Control and Prevention’s Water Fluoridation Reporting System were merged with dental examination data from 10 y of National Health and Nutrition Examination Surveys (1999 to 2004 and 2011 to 2014). Dental caries experience in the primary dentition (decayed and filled tooth surfaces [dfs]) was calculated for 7,000 children aged 2 to 8 y and in the permanent dentition (decayed, missing, and filled tooth surfaces [DMFS]) for 12,604 children and adolescents aged 6 to 17 y. Linear regression models estimated associations between % CWF and dental caries experience with adjustment for sociodemographic characteristics: age, sex, race/ethnicity, rural-urban location, head-of-household education, and period since last dental visit. Sensitivity analysis excluded counties fluoridated after 1998. In unadjusted analysis, caries experience in the primary dentition was lower in counties with ≥75%CWF (mean dfs = 3.3, 95% confidence limits [CL]=2.8, 3.7) than in counties with <75%CWF (mean dfs =4.6, 95%CL=3.9, 5.4), a prevented fraction of 30% (95%CL = 11, 48). The difference was also statistically significant, though less pronounced, in the permanent dentition: mean DMFS (95%CL) was 2.2 (2.0, 2.4) and 1.9 (1.8, 2.1), respectively, representing a prevented fraction of 12% (95%CL=1, 23). Statistically significant associations likewise were seen when %CWF was modeled as a continuum, and differences tended to increase in covariate-adjusted analysis and in sensitivity analysis. These findings confirm a substantial caries-preventive benefit of CWF for U.S. children and that the benefit is most pronounced in primary teeth.
Response To Fluoridation Opponents Criticisms of 2017 NTP Study
In the below letter to the editor of Neurotoxicity Research, Dr. Jean Harry, lead contact researcher for the 2017 McPherson, et al NTP study, responds to criticisms made by fluoridation opponents: July 5, 2018 Dear Dr. Kostrzewa I am writing in response to a letter...
National Toxicology Program: An Evaluation of Neurotoxicity Following Fluoride Exposure from Gestational Through Adult Ages in Long-Evans Hooded Rats
No exposure-related pathology was observed in the heart, liver, kidney, testes, seminal vesicles, or epididymides. Mild inflammation in the prostate gland was observed at 20 ppm F−. No evidence of neuronal death or glial activation was observed in the hippocampus at 20 ppm F−.
A Canadian Population-based Study of the Relationship between Fluoride Exposure and Indicators of Cognitive and Thyroid Functioning; Implications for Community Water Fluoridation
Abstract: Concerns exist regarding potential harms of community water fluoridation. The study objective was to examine the association between fluoride exposure and indicators of two health outcomes for which concerns have been expressed, cognitive and thyroid...
Can Fluoridation Affect Lead (II) In Potable Water? Hexafluorosilicate and Fluoride Equilibria In Aqueous Solution
Overall we conclude that no credible evidence exists to show that water fluoridation has any quantifiable effects on the solubility, bioavailability, bioaccumulation or reactivity of lead (0) or lead (II) compounds. The governing factots are the concentrations of a...