Fluoride Exposure and Childhood Osteosarcoma: A Case-Control Study

“Fluoride exposure does not increase the risk of osteosarcoma and may be protective in males.  The protective effect may not be directly due to fluoride exposure but may be due to other factors associated with good dental hygiene.  There is also a biologic plausability for a protective effect.”

KittyH. Gelberg, PhD, MPH, Edward F. Fitzgerald, PhD, Syni-an Hwang, PhD, andRobertDubrow,MD, PhD(Am J  Public Health 1995;85:1678-1683)Osteosarcoma1995 Gelberg Fluoride Exposure and childhood Osteosarcoma – A Case-Control Study

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